THE BASIC PRINCIPLES OF MAKATUSSIN SYROP

desvenlafaxine will improve the stage or effect of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an eye on. Desvenlafaxine inhibits CYP2D6; with bigger desvenlafaxine doses (ie, 400 mg) lower the CYP2D6 substrate dose by approximately 50%; no dosage adjustment essential with desvenlafaxine doses 7 consecutive days straight